© 2000 - 2014 Virginia Bioinformatics Institute
Wednesday, 23 April 2014

Data Analysis Core
VBI Data Analysis Core

VBI's Data Analysis Core (DAC) is a dedicated multi-user resource that provides state-of-the-art data analysis support for biologically related research.  The DAC was created to remove data analysis as an obstacle to performing the highly complex and data-intensive experiments required to solve modern problems in life science research.  We have experienced staff available to provide guidance and support in designing and executing on properly powered and controlled experiments. 


At the DAC, a wide range of services are available to solve the data analysis bottleneck.  We offer services ranging from training and self-serve workstations preloaded with necessary software to full service project support.  Next generation sequencing projects include the analysis, assembly, and annotation of genomic sequence information including protein function prediction, variant/allele discovery, and expression analysis (CHIP-seq, RNA-seq, DNA-reseq, SNP-seq, and others).  For gene expression (Affymetrix or custom), we offer statistical expression analysis, normalization, quality analysis, filtering customized to the experimental design, hierarchical clustering, and, when appropriate, function analysis.  Custom array design for both oligonucleotide and proteomics arrays as well as target design for deep sequencing experiments are also available. For genomic, transcriptomics, and proteomics, we offer statistical analysis, pathway and GO analysis. All services result in manuscript-ready figures and text. 


Important Support Information

Services Include:

Custom Services -- Ask Us

Every experiment has elements that are unique; call us to discuss custom analysis.

Sequence Assembly

  • Support for Illumina, PacBio, Ion Torrent, and 454
  • Trimming
  • Assembly
  • Mapping to reference
  • Gap discovery

Sequence Annotation

  • Gene prediction
  • Protein function prediction
  • Variation discovery/allele analysis (CNV, SNP)

Expression Analysis

  • Gene chip (Affymetrix)
  • Next generation transcriptome
  • Mass spectrometry data analysis
  • Clustering


  • Experimental design assistance
  • Pathway analysis
  • GO annotation
  • Sub-cellular location prediction
  • Links to biostatistical help with on-site statisticians
  • Custom oligonucleotide and proteomics array design
  • Target design for enrichment and deep sequencing

What can we do for you?

For more information: dac@vbi.vt.edu, 540-231-2777