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Purwantini,
Endang
, Ph.D
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| Faculty
- Purwantini, Endang
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Senior Research Associate
Phone: (540) 231-4395
Email: epurwant@vt.edu
Fax: 540-231-2606
Microbial Diversity Group |
Publications
| Mycobacterial Research Program
Professional Preparation
- The University of Iowa, Microbiology, Ph.D, 1997
- The University of Iowa, Microbiology, MS, 1993
- University of Illinois at Urbana-Champaign, Microbiology, Postodoc, 1998
- University of Iowa, Microbiology, Postdoc, 1997
Research Interests - Role of Coenzyme F420 in mycobacteria
Biography
      Endang Purwantini is a senior research associate at the Virginia Bioinformatics Institute. She has a pharmacy degree from School of Pharmacy at the Institut Teknologi Bandung, Indonesia and earned her Ph.D. in Microbiology from the University of Iowa in 1997. She received her post-doctoral training in the laboratories of Dr. Lacy Daniels at the University of Iowa and Dr. Ralph S. Wolfe at the University of Illinois. She was faculty a member at the School of Pharmacy at Institut Teknologi Bandung (ITB) in Indonesia in 1985-2002 and served as Senior Research Scientist (Microbial Biochemistry) at the Inter University Center of the ITB in 1987-2002. In 2002 she joined VBI. Her research interests include molecular biology, microbial genetics, and enzymology of the mycobacteria; more specifically on coenzyme F420-dependent reactions. She won the 1999 Toray Science and Technology Award in Indonesia from the Indonesia Toray Science Foundation.
Selected Publications
Hasan MR, Rahman M, Jaques S, Purwantini E, Daniels L. Glucose 6-phosphate accumulation in mycobacteria: implications for a novel F420-dependent anti-oxidant defense system. J Biol Chem. 2010;285:19135–19144.
Purwantini E, Mukhopadhyay B. Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage. Proc Natl Acad Sci U S A. 2009;106:6333–6338.
Purwantini E, Daniels L. Molecular analysis of the gene encoding F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis. J Bacteriol. 1998;180:2212–2219.
Purwantini E, Daniels L. Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis. J Bacteriol. 1996;178:2861–2866.
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