Virginia Bioinformatics Institute

Wednesday, 16 May 2012

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Mittelman, David , Ph.D.

Faculty - Publications - Mittelman, David

Associate Professor, Virginia Bioinformatics Institute
Associate Professor, Department of Biological Sciences, Virginia Tech

Phone: (540) 231-6430
Email:mittelma@vbi.vt.edu
Fax: 540-231-2606

Administrative Specialist: Patricia Boyle
Phone: (540) 231-7254
Email: paboyle@vbi.vt.edu
Fax:540-231-2606

Personal_Page | Genetics and Genomic Medicine Lab

Publications:

2012

Fondon JW 3rd, Martin A, Richards S, Gibbs RA, Mittelman D. Analysis of Microsatellite Variation in Drosophila melanogaster with Population-Scale Genome Sequencing. PLoS One. 2012;7:12.

Li JW, Schmieder R, Ward RM, Delenick J, Olivares EC, Mittelman D. SEQanswers: An open access community for collaboratively decoding genomes. Bioinformatics. 2012;13:13.

Mackay TFC RS Stone EA Barbadilla A Ayroles JF Zhu D Casillas S Han Y Magwire MM Cridland JM et al. The Drosophila Genetic Reference Panel: A Community Resource for Analysis of Population Genomics and Quantitative Traits. Nature. 2012;482(7384):173–8.

2011

Fonville NC, Ward RM, Mittelman D. Stress-induced modulators of repeat instability and genome evolution. J Mol Microbiol Biotechnol. 2011;21:36–44. http://www.ncbi.nlm.nih.gov/pubmed/22248541

2010

Mittelman D, Sykoudis K, Hersh M, Lin Y, Wilson JH. Hsp90 modulates CAG repeat instability in human cells. Cell Stress Chaperones. 2010;15:753–759. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20373063

Mittelman D, Wilson JH. Stress, genomes, and evolution. Cell Stress Chaperones. 2010;15:463–466. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20521130

2009

Mittelman D, Moye C, Morton J, et al. Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells. Proc Natl Acad Sci U S A. 2009;106:9607–9612. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19482946

2006

Morgan DH, Kristensen DM, Mittelman D, Lichtarge O. ET viewer: an application for predicting and visualizing functional sites in protein structures. Bioinformatics. 2006;22:2049–2050. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16809388

2004

Gorbunova V, Seluanov A, Mittelman D, Wilson JH. Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. Hum Mol Genet. 2004;13:2979–2989. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15459182

Seluanov A, Mittelman D, Pereira-Smith OM, Wilson JH, Gorbunova V. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proc Natl Acad Sci U S A. 2004;101:7624–7629. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15123826

2003

Mittelman D, Sadreyev R, Grishin N. Probabilistic scoring measures for profile-profile comparison yield more accurate short seed alignments. Bioinformatics. 2003;19:1531–1539. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12912834

2002

Balog RP, de Souza YE, Tang HM, et al. Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays. Anal Biochem. 2002;309:301–310. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12413464

Kulkarni AV, Williams NS, Lian Y, et al. ARROGANT: an application to manipulate large gene collections. Bioinformatics. 2002;18:1410–1417. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12424110

Luebke KJ BRP Mittelman D Garner HR. Digital Optical Chemistry: A Novel System for the Rapid Fabrication of Custom Oligonucleotide Arrays. In: Kordal R UA Law W, ed. Microfabricated Sensors, Application of Optical Technology for DNA Analysis. Washington, D.C.: American Chemical Society; 2002.

Wren JD, Mittelman DA, Garner HR. SIGNAL-Sequence Information and GeNomic AnaLysis. Comput Methods Programs Biomed. 2002;68:177–181. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11932033

2000

Pertsemlidis A, Pande A, Miller B, et al. PANORAMA: an integrated Web-based sequence analysis tool and its role in gene discovery. Genomics. 2000;70:300–306. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11161780