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Professor, Virginia Bioinformatics Institute
Professor, Department of Statistics, Virginia Tech
Adjunct Professor, Department of Cancer Biology, Biostatistics Core
Member, Comprehensive Cancer Center, Wake Forest University School of
Medicine, Winston-Salem, NC
Adjunct Professor, Virginia Tech Carilion School of Medicine
Phone: (540) 231-3135
Email:inah@vbi.vt.edu
Fax: 540-231-2606
Administrative Specialist: Kimberly Clifton
Phone: (540) 231-9882
Email: kimvt05@vbi.vt.edu
Fax:540-231-2606
Personal_Page
| Hoeschele Research Group
| SysGenSIM
Publications:
Galindo CL, McIver LJ, Tae H, et al. Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature. Genes Chromosomes Cancer. 2011;50(4):275–283. http://www.ncbi.nlm.nih.gov/pubmed/21319262
Kangas-Kontio T, Kakko S, Tamminen M, et al. Genome scan for loci regulating HDL cholesterol levels in Finnish extended pedigrees with early coronary heart disease. Eur J Hum Genet. 2010;18(5):604–613. http://www.ncbi.nlm.nih.gov/pubmed/19935834
Zou F, Huang H, Lee S, Hoeschele I. Nonparametric Bayesian variable selection with applications to multiple quantitative trait loci mapping with epistasis and gene-environment interaction. Genetics. 2010;186(1):385–394. http://www.ncbi.nlm.nih.gov/pubmed/20551445
Liu B, Hoeschele I, de la Fuente A. Inferring gene regulatory networks from genetical genomics data. In: Das S, Caragea D, Hsu WH, Welsh SM, eds. Computational methodologies in gene regulatory networks. IGI Global; 2009:In press.
Bao L, Hoeschele I. Quality Assessment for Short Oligonucleotide Microarray Data. Comment. Technometrics. 2008;50:268–270.
Hoeschele I. Mapping quantitative trait loci in outbred populations. In: Balding DJ, Bishop M, Cannings C, eds. Handbook of statistical genetics. New York: Wiley; 2007:623–677.
Stock KF, Distl O, Hoeschele I. Influence of priors in Bayesian estimation of genetic parameters for multivariate threshold models using Gibbs sampling. Genetics Selection Evolution. 2007;39:123–137.
Stock KF, Distl O, Hoeschele I. Bayesian estimation of genetic parameters for multivariate threshold and continuous phenotypes and molecular genetic data in simulated horse populations using Gibbs sampling. BMC Genet. 2007;8:19. http://www.hubmed.org/display.cgi?uids=17490471
Betthauser JM, Pfister-Genskow M, Xu HZ, et al. Nucleoplasmin facilitates reprogramming and in vivo development of bovine nuclear transfer embryos. Molecular Reproduction and Development. 2006;73:977–986.
Bing N, Hoeschele I, Ye KY, Eilertsen KJ. Finite mixture model analysis of microarray expression data on samples of uncertain biological type with application to reproductive efficiency. Veterinary Immunology and Immunopathology. 2005;105:187–196.
Gao G, Hoeschele I. A note on a conditional enumeration haplotyping method in pedigrees. New York: Springer-Verlag; 2005. Lecture Notes in Bioinformatics.
Gao GM, Hoeschele I. Approximating identity-by-descent matrices using multiple haplotype configurations on pedigrees. Genetics. 2005;171:365–376.
Hoeschele I, Li H. A note on joint versus gene-specific mixed model analysis of microarray gene expression data. Biostatistics. 2005;6:183–186.
Pfister-Genskow M, Myers C, Childs LA, et al. Identification of differentially expressed genes in individual bovine preimplantation embryos produced by nuclear transfer: Improper reprogramming of genes required for development. Biology of Reproduction. 2005;72:546–555.
de la Fuente A, Bing N, Hoeschele I, Mendes P. Discovery of meaningful associations in genomic data using partial correlation coefficients. Bioinformatics. 2004;20:3565–3574.
Gao GM, Hoeschele I, Sorensen P, Du FX. Conditional probability methods for haplotyping in pedigrees. Genetics. 2004;167:2055–2065.
Freyer G, Sorensen P, Kuhn C, Weikard R, Hoeschele I. Search for pleiotropic QTL on chromosome BTA6 affecting yield traits of milk production. Journal of Dairy Science. 2003;86:999–1008.
Kakko S, Kelloniemi J, von Rohr P, et al. ATP-binding cassette transporter A1 locus is not a major determinant of HDL-C levels in a population at high risk for coronary heart disease. Atherosclerosis. 2003;166:285–290.
Du F-X, Sorensen P, Thaller G, Hoeschele I. Joint linkage disequilibrium and linkage mapping of quantitative trait loci. Proceedings of the 7th World Congress of Genetics Applied to Livestock Production. 2002;32:661–668.
Freyer G, Kuhn C, Weikard R, Zhang Q, Mayer M, Hoeschele I. Multiple QTL on chromosome six in dairy cattle affecting yield and content traits. Journal of Animal Breeding and Genetics. 2002;119:69–82.
Stricker C, Schelling M, Du F-X, Hoeschele I, Fern. A comparison of efficient genotype samplers for complex pedigrees and multiple linked loci.; 2002:637–644. Proceedings of the 7th World Congress on Genetics Applied to Livestock Production 32.
von Rohr P, Hoeschele I. Bayesian QTL mapping using skewed Student-t distributions. Genetics Selection Evolution. 2002;34:1–21.
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